HCSGD entry for EMR2
1. General information
| Official gene symbol | EMR2 |
|---|---|
| Entrez ID | 30817 |
| Gene full name | egf-like module containing, mucin-like, hormone receptor-like 2 |
| Other gene symbols | CD312 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007155 | Cell adhesion | IMP | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016477 | Cell migration | IMP | biological_process |
| GO:0031256 | Leading edge membrane | IDA | cellular_component |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0035374 | Chondroitin sulfate binding | IMP | molecular_function |
| GO:0071621 | Granulocyte chemotaxis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0020917480 | 0.9778553474 | 0.1232724832 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0344396267 |
| GSE13712_SHEAR | Down | -0.0021556801 |
| GSE13712_STATIC | Up | 0.0534749350 |
| GSE19018 | Down | -0.0566725081 |
| GSE19899_A1 | Up | 0.6023698996 |
| GSE19899_A2 | Up | 2.2690477321 |
| PubMed_21979375_A1 | Up | 2.2009176934 |
| PubMed_21979375_A2 | Up | 2.7451760888 |
| GSE35957 | Down | -0.0837620393 |
| GSE36640 | Down | -0.1053728741 |
| GSE54402 | Up | 1.8068391581 |
| GSE9593 | Down | -0.1283214735 |
| GSE43922 | Up | 3.1847280854 |
| GSE24585 | Up | 0.1383154379 |
| GSE37065 | Up | 0.0619353083 |
| GSE28863_A1 | Up | 0.3439453151 |
| GSE28863_A2 | Up | 0.1881835558 |
| GSE28863_A3 | Down | -0.0691062584 |
| GSE28863_A4 | Up | 0.1906940312 |
| GSE48662 | Down | -0.0879691559 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027542 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050536 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
