HCSGD entry for ERVW-1
1. General information
| Official gene symbol | ERVW-1 |
|---|---|
| Entrez ID | 30816 |
| Gene full name | endogenous retrovirus group W, member 1 |
| Other gene symbols | ENV ENVW ERVWE1 HERV-7q HERV-W-ENV HERV7Q HERVW HERVWENV |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006949 | Syncytium formation | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019031 | Viral envelope | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5122433038 | 0.7012578891 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3235029734 |
| GSE13712_SHEAR | Down | -0.2874092793 |
| GSE13712_STATIC | Down | -0.0120049999 |
| GSE19018 | Down | -0.1090043594 |
| GSE19899_A1 | Up | 0.1396537589 |
| GSE19899_A2 | Up | 0.2387884226 |
| PubMed_21979375_A1 | Down | -0.1863898975 |
| PubMed_21979375_A2 | Up | 0.1906561983 |
| GSE35957 | Down | -0.0579764908 |
| GSE36640 | Down | -0.0746824676 |
| GSE54402 | Up | 0.0623832252 |
| GSE9593 | Up | 0.0291425404 |
| GSE43922 | Up | 0.0124774908 |
| GSE24585 | Up | 0.0765547237 |
| GSE37065 | Up | 0.0626106436 |
| GSE28863_A1 | Down | -0.2018599288 |
| GSE28863_A2 | Down | -0.0714321350 |
| GSE28863_A3 | Up | 0.2509849464 |
| GSE28863_A4 | Up | 0.0212835901 |
| GSE48662 | Down | -0.0320923747 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26029982 | Surprisingly, p53 disabled tumor cells could be forced into senescence by expression of a mutant allele of the nuclear envelope protein lamin A |
| 24186980 | Cell fusion induced by ERVWE1 or measles virus causes cellular senescence |
| 22541428 | Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies |
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