HCSGD entry for CFHR1
1. General information
| Official gene symbol | CFHR1 |
|---|---|
| Entrez ID | 3078 |
| Gene full name | complement factor H-related 1 |
| Other gene symbols | CFHL CFHL1 CFHL1P CFHR1P FHR1 H36-1 H36-2 HFL1 HFL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0006956 | Complement activation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3121428365 | 0.9473011246 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | Down | -0.3131071360 |
| GSE24585 | Down | -0.0395504399 |
| GSE37065 | Up | 0.2297022626 |
| GSE28863_A1 | Up | 0.0504940634 |
| GSE28863_A2 | Up | 0.7967149993 |
| GSE28863_A3 | Up | 0.2399191912 |
| GSE28863_A4 | Down | -0.0365674514 |
| GSE48662 | Down | -0.0455792483 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25015975 | Human fetal (HFL-1) and adult lung fibroblasts were exposed to CSE for 14 days |
| 25015975 | HFL-1 proliferation was inhibited by CSE and nearly half of the CSE-exposed cells were SA beta-gal positive after 14 days exposure, whereas 33% of adult lung fibroblasts were SA beta-gal positive in response to 10% CSE exposure |
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