HCSGD entry for HCRTR1
1. General information
| Official gene symbol | HCRTR1 |
|---|---|
| Entrez ID | 3061 |
| Gene full name | hypocretin (orexin) receptor 1 |
| Other gene symbols | OX1R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007631 | Feeding behavior | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016499 | Orexin receptor activity | IEA | molecular_function |
| GO:0017046 | Peptide hormone binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6053632271 | 0.8492028076 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0413941284 |
| GSE13712_SHEAR | Down | -0.1235104815 |
| GSE13712_STATIC | Down | -0.0328285905 |
| GSE19018 | Up | 0.1415041499 |
| GSE19899_A1 | Down | -0.0180869887 |
| GSE19899_A2 | Down | -0.0597317829 |
| PubMed_21979375_A1 | Down | -0.2669557776 |
| PubMed_21979375_A2 | Up | 0.0716779954 |
| GSE35957 | Up | 0.0176806576 |
| GSE36640 | Up | 0.1805192608 |
| GSE54402 | Down | -0.0217411364 |
| GSE9593 | Up | 0.0499321109 |
| GSE43922 | Up | 0.0253425796 |
| GSE24585 | Up | 0.0963147030 |
| GSE37065 | Up | 0.0717639857 |
| GSE28863_A1 | Down | -0.0316729393 |
| GSE28863_A2 | Down | -0.0104992470 |
| GSE28863_A3 | Up | 0.3584575776 |
| GSE28863_A4 | Up | 0.0540613311 |
| GSE48662 | Up | 0.2940897013 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018468 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
