HCSGD entry for SH3KBP1

1. General information

Official gene symbolSH3KBP1
Entrez ID30011
Gene full nameSH3-domain kinase binding protein 1
Other gene symbolsCD2BP3 CIN85 GIG10 HSB-1 HSB1 MIG18
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingNASbiological_process
GO:0008360Regulation of cell shapeIMPbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016477Cell migrationIMPbiological_process
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0043005Neuron projectionIEAcellular_component
GO:0045202SynapseIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00076094750.86489036890.07733166021.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.0525366882
GSE13712_SHEARUp1.1563756807
GSE13712_STATICUp0.9464242256
GSE19018Up0.8220368294
GSE19899_A1Up1.3088083364
GSE19899_A2Up1.2650538921
PubMed_21979375_A1Up0.6368083216
PubMed_21979375_A2Up0.7070107095
GSE35957Down-0.3521282666
GSE36640Up1.2814500181
GSE54402Up1.0687284360
GSE9593Up0.1313192151
GSE43922Up0.3669501949
GSE24585Down-0.7872463905
GSE37065Up0.1132064499
GSE28863_A1Down-0.6331663981
GSE28863_A2Down-0.4082200859
GSE28863_A3Up0.5126855515
GSE28863_A4Up0.0071325485
GSE48662Up0.2495483022

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1914-5pMIMAT0007889MIRT035790CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.