HCSGD entry for EFEMP2
1. General information
| Official gene symbol | EFEMP2 |
|---|---|
| Entrez ID | 30008 |
| Gene full name | EGF containing fibulin-like extracellular matrix protein 2 |
| Other gene symbols | ARCL1B FBLN4 MBP1 UPH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | IEA | molecular_function |
| GO:0005201 | Extracellular matrix structural constituent | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005604 | Basement membrane | TAS | cellular_component |
| GO:0007596 | Blood coagulation | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9252589073 | 0.0009321492 | 0.9999902473 | 0.0574592506 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7297110386 |
| GSE13712_SHEAR | Down | -0.5895229200 |
| GSE13712_STATIC | Down | -0.6450417376 |
| GSE19018 | Up | 0.6955684281 |
| GSE19899_A1 | Down | -2.3556685126 |
| GSE19899_A2 | Down | -1.2518804257 |
| PubMed_21979375_A1 | Down | -2.4719559007 |
| PubMed_21979375_A2 | Down | -2.7188183885 |
| GSE35957 | Down | -0.0536195685 |
| GSE36640 | Up | 0.7374946511 |
| GSE54402 | Down | -1.1042699031 |
| GSE9593 | Up | 0.2843336628 |
| GSE43922 | Down | -1.6188718465 |
| GSE24585 | Up | 0.2121432638 |
| GSE37065 | Down | -0.1324764009 |
| GSE28863_A1 | Down | -0.0657054162 |
| GSE28863_A2 | Down | -0.2774660242 |
| GSE28863_A3 | Down | -0.2930438909 |
| GSE28863_A4 | Down | -0.2307626022 |
| GSE48662 | Up | 0.1779483431 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-346 | MIMAT0000773 | MIRT000076 | Microarray//qRT-PCR | Functional MTI (Weak) | 16822819 |
| hsa-miR-346 | MIMAT0000773 | MIRT000076 | Western blot;Other | Functional MTI | 21611196 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021872 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
