HCSGD entry for TNPO2
1. General information
| Official gene symbol | TNPO2 |
|---|---|
| Entrez ID | 30000 |
| Gene full name | transportin 2 |
| Other gene symbols | IPO3 KPNB2B TRN2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0008139 | Nuclear localization sequence binding | TAS | molecular_function |
| GO:0008536 | Ran GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5779356369 | 0.2214483264 | 0.9999902473 | 0.9051246739 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0080100828 |
| GSE13712_SHEAR | Up | 0.0915712534 |
| GSE13712_STATIC | Down | -0.0483910494 |
| GSE19018 | Up | 0.0076565194 |
| GSE19899_A1 | Down | -0.2568098893 |
| GSE19899_A2 | Down | -0.0945890948 |
| PubMed_21979375_A1 | Down | -0.3466790502 |
| PubMed_21979375_A2 | Down | -0.4117952682 |
| GSE35957 | Down | -0.1455306363 |
| GSE36640 | Down | -0.0394701335 |
| GSE54402 | Down | -0.0353460414 |
| GSE9593 | Up | 0.0451342307 |
| GSE43922 | Down | -0.0896538383 |
| GSE24585 | Down | -0.3948523088 |
| GSE37065 | Down | -0.1400932334 |
| GSE28863_A1 | Up | 0.8752765069 |
| GSE28863_A2 | Up | 0.8379915976 |
| GSE28863_A3 | Up | 0.1520428229 |
| GSE28863_A4 | Down | -0.1337956418 |
| GSE48662 | Up | 0.1371487772 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT019238 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021089 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021306 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT021490 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039785 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-598-3p | MIMAT0003266 | MIRT040490 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040668 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050201 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
