HCSGD entry for GUCY2D
1. General information
| Official gene symbol | GUCY2D |
|---|---|
| Entrez ID | 3000 |
| Gene full name | guanylate cyclase 2D, membrane (retina-specific) |
| Other gene symbols | CORD5 CORD6 CYGD GUC1A4 GUC2D LCA LCA1 RCD2 RETGC-1 ROS-GC1 ROSGC retGC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004383 | Guanylate cyclase activity | IEA | molecular_function |
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005640 | Nuclear outer membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007168 | Receptor guanylyl cyclase signaling pathway | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0016056 | Rhodopsin mediated signaling pathway | TAS | biological_process |
| GO:0022400 | Regulation of rhodopsin mediated signaling pathway | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0097381 | Photoreceptor disc membrane | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7515815357 | 0.6216325292 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0565746474 |
| GSE13712_SHEAR | Down | -0.1749822360 |
| GSE13712_STATIC | Down | -0.1429398166 |
| GSE19018 | Up | 0.0724932517 |
| GSE19899_A1 | Up | 0.0036987391 |
| GSE19899_A2 | Down | -0.0897728905 |
| PubMed_21979375_A1 | Down | -0.1642766485 |
| PubMed_21979375_A2 | Down | -0.3272829053 |
| GSE35957 | Up | 0.2963316668 |
| GSE36640 | Up | 0.2394926595 |
| GSE54402 | Up | 0.0418680002 |
| GSE9593 | Down | -0.0861103698 |
| GSE43922 | Up | 0.1307424742 |
| GSE24585 | Up | 0.0244526588 |
| GSE37065 | Down | -0.1178867246 |
| GSE28863_A1 | Down | -0.2048378359 |
| GSE28863_A2 | Down | -0.0392991359 |
| GSE28863_A3 | Up | 0.3192857334 |
| GSE28863_A4 | Up | 0.1692013401 |
| GSE48662 | Down | -0.0102519874 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord

