HCSGD entry for PSAT1
1. General information
| Official gene symbol | PSAT1 |
|---|---|
| Entrez ID | 29968 |
| Gene full name | phosphoserine aminotransferase 1 |
| Other gene symbols | EPIP PSA PSAT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004648 | O-phospho-L-serine:2-oxoglutarate aminotransferase activity | NAS TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006564 | L-serine biosynthetic process | NAS TAS | biological_process |
| GO:0008615 | Pyridoxine biosynthetic process | NAS | biological_process |
| GO:0008652 | Cellular amino acid biosynthetic process | TAS | biological_process |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4339311728 | 0.0006200600 | 0.9999902473 | 0.0464551136 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0259620578 |
| GSE13712_SHEAR | Up | 0.3306686714 |
| GSE13712_STATIC | Down | -0.5976822202 |
| GSE19018 | Up | 1.6026556648 |
| GSE19899_A1 | Down | -0.6147697331 |
| GSE19899_A2 | Down | -2.0769070412 |
| PubMed_21979375_A1 | Down | -1.0368438128 |
| PubMed_21979375_A2 | Down | -3.7776486811 |
| GSE35957 | Down | -0.2660530627 |
| GSE36640 | Down | -0.9203449595 |
| GSE54402 | Down | -1.8886728821 |
| GSE9593 | Up | 0.7399251778 |
| GSE43922 | Down | -0.6497415347 |
| GSE24585 | Down | -0.7101154917 |
| GSE37065 | Down | -1.0993537478 |
| GSE28863_A1 | Down | -0.0112345904 |
| GSE28863_A2 | Down | -0.2283154564 |
| GSE28863_A3 | Up | 0.2351119174 |
| GSE28863_A4 | Down | -0.1554247896 |
| GSE48662 | Up | 0.5089733894 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001427 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020766 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023797 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029458 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041083 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043679 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046060 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052767 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
