HCSGD entry for DMGDH
1. General information
| Official gene symbol | DMGDH |
|---|---|
| Entrez ID | 29958 |
| Gene full name | dimethylglycine dehydrogenase |
| Other gene symbols | DMGDHD ME2GLYDH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004047 | Aminomethyltransferase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | NAS | cellular_component |
| GO:0006544 | Glycine metabolic process | IMP | biological_process |
| GO:0006546 | Glycine catabolic process | IEA | biological_process |
| GO:0006579 | Amino-acid betaine catabolic process | IEA | biological_process |
| GO:0009055 | Electron carrier activity | NAS | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0019695 | Choline metabolic process | NAS | biological_process |
| GO:0047865 | Dimethylglycine dehydrogenase activity | IMP | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4977175677 | 0.8215648494 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1514975400 |
| GSE13712_SHEAR | Down | -0.0816445696 |
| GSE13712_STATIC | Up | 0.1825368411 |
| GSE19018 | Down | -0.0365982853 |
| GSE19899_A1 | Down | -0.0677999832 |
| GSE19899_A2 | Down | -0.0528088478 |
| PubMed_21979375_A1 | Up | 0.2842893611 |
| PubMed_21979375_A2 | Up | 0.0003124157 |
| GSE35957 | Up | 0.0954898736 |
| GSE36640 | Up | 0.1093868813 |
| GSE54402 | Down | -0.0711070656 |
| GSE9593 | Up | 0.2100570093 |
| GSE43922 | Up | 0.0163694526 |
| GSE24585 | Down | -0.0185978161 |
| GSE37065 | Up | 0.0286077565 |
| GSE28863_A1 | Down | -0.0489885135 |
| GSE28863_A2 | Up | 0.0528375244 |
| GSE28863_A3 | Up | 0.1542335034 |
| GSE28863_A4 | Up | 0.0847066284 |
| GSE48662 | Down | -0.0206344663 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016761 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021745 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
