HCSGD entry for GYPA


1. General information

Official gene symbolGYPA
Entrez ID2993
Gene full nameglycophorin A (MNS blood group)
Other gene symbolsCD235a GPA GPErik GPSAT HGpMiV HGpMiXI HGpSta(C) MN MNS PAS-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001618Virus receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007016Cytoskeletal anchoring at plasma membraneIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0047484Regulation of response to osmotic stressIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90154927620.54557770220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0008375454
GSE13712_SHEARDown-0.0568775710
GSE13712_STATICDown-0.0414525182
GSE19018Up0.0591831443
GSE19899_A1Up0.0723562271
GSE19899_A2Down-0.0861807093
PubMed_21979375_A1Up0.1393028216
PubMed_21979375_A2Up0.0522584559
GSE35957Up0.1247365433
GSE36640Up0.1166670653
GSE54402Down-0.0439609933
GSE9593Down-0.0253381202
GSE43922Down-0.1350778728
GSE24585Up0.1277593949
GSE37065Down-0.0573338646
GSE28863_A1Down-0.0982757277
GSE28863_A2Down-0.2898214496
GSE28863_A3Down-0.2594103228
GSE28863_A4Down-0.0763293365
GSE48662Up0.1121940040

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23478225Finally, the micromechanical properties determined by atomic force microscopy (AFM) indentation varied in the range from 6 GPa (PEU) to 13 GPa (PEI)
8866734It is thought that En(a-) red blood cell ageing is accompanied by elimination of some sialoglycoconjugates which have affinity for LPA, Con A, WGA and BPA, whereas En(a-) red blood cells lack glycophorin A
65729291, actin, glycophorin A, and intact or desialylated sialoglycoprotein periodic acid/Schiff (PAS) staining bands 1-4 containing glycophorins A, B, and C did not inhibit phagocytosis
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