HCSGD entry for EPN1
1. General information
| Official gene symbol | EPN1 |
|---|---|
| Entrez ID | 29924 |
| Gene full name | epsin 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007219 | Notch signaling pathway | IEA | biological_process |
| GO:0007565 | Female pregnancy | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IEA | molecular_function |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0042059 | Negative regulation of epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0048568 | Embryonic organ development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7534946203 | 0.4454544356 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0338542294 |
| GSE13712_SHEAR | Up | 0.0331511053 |
| GSE13712_STATIC | Down | -0.1342590392 |
| GSE19018 | Up | 0.1388324832 |
| GSE19899_A1 | Down | -0.0972597210 |
| GSE19899_A2 | Up | 0.2463050583 |
| PubMed_21979375_A1 | Down | -0.2357102956 |
| PubMed_21979375_A2 | Up | 0.2893315584 |
| GSE35957 | Down | -0.0593856183 |
| GSE36640 | Up | 0.0596942318 |
| GSE54402 | Up | 0.2111517199 |
| GSE9593 | Down | -0.1633037437 |
| GSE43922 | Up | 0.1267920744 |
| GSE24585 | Down | -0.0463605891 |
| GSE37065 | Down | -0.2204699131 |
| GSE28863_A1 | Down | -0.0046061181 |
| GSE28863_A2 | Up | 0.0501909833 |
| GSE28863_A3 | Down | -0.0824337933 |
| GSE28863_A4 | Down | -0.1654909083 |
| GSE48662 | Down | -0.3128319051 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,4-Diethylene Dioxide | DB03316 | EXPT01208 |
| D-Myo-Inositol-1,4,5-Triphosphate | DB03401 | EXPT01811 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037415 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038071 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
