HCSGD entry for GPSM2
1. General information
| Official gene symbol | GPSM2 |
|---|---|
| Entrez ID | 29899 |
| Gene full name | G-protein signaling modulator 2 |
| Other gene symbols | CMCS DFNB82 LGN PINS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000132 | Establishment of mitotic spindle orientation | IEA | biological_process |
| GO:0005092 | GDP-dissociation inhibitor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0060487 | Lung epithelial cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7534868394 | 0.0005814255 | 0.9999902473 | 0.0452772189 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4860880042 |
| GSE13712_SHEAR | Down | -0.3267467195 |
| GSE13712_STATIC | Down | -0.5956573347 |
| GSE19018 | Up | 0.0771417043 |
| GSE19899_A1 | Down | -0.3481443571 |
| GSE19899_A2 | Down | -1.6618586572 |
| PubMed_21979375_A1 | Down | -0.3553184674 |
| PubMed_21979375_A2 | Down | -1.7966171504 |
| GSE35957 | Down | -1.9895828748 |
| GSE36640 | Down | -1.8468484492 |
| GSE54402 | Down | -0.5819126939 |
| GSE9593 | Down | -0.5620516623 |
| GSE43922 | Down | -1.1373004337 |
| GSE24585 | Up | 0.3436701937 |
| GSE37065 | Down | -0.2620989445 |
| GSE28863_A1 | Up | 0.5806621325 |
| GSE28863_A2 | Up | 2.1492422237 |
| GSE28863_A3 | Down | -1.0312216840 |
| GSE28863_A4 | Up | 0.0295290565 |
| GSE48662 | Down | -1.5924293840 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002524 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024301 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026240 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
