HCSGD entry for SNX10
1. General information
| Official gene symbol | SNX10 |
|---|---|
| Entrez ID | 29887 |
| Gene full name | sorting nexin 10 |
| Other gene symbols | OPTB8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005545 | 1-phosphatidylinositol binding | IMP | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0007032 | Endosome organization | IMP | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030316 | Osteoclast differentiation | IEA ISS | biological_process |
| GO:0031313 | Extrinsic component of endosome membrane | IDA | cellular_component |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0042384 | Cilium assembly | IMP | biological_process |
| GO:0051117 | ATPase binding | IPI | molecular_function |
| GO:0061512 | Protein localization to cilium | IMP | biological_process |
| GO:0071539 | Protein localization to centrosome | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0402595342 | 0.9337584780 | 0.4503490013 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2002019109 |
| GSE13712_SHEAR | Up | 0.8122594658 |
| GSE13712_STATIC | Up | 1.7549501573 |
| GSE19018 | Up | 0.2194388782 |
| GSE19899_A1 | Down | -0.0291059508 |
| GSE19899_A2 | Down | -0.1005752317 |
| PubMed_21979375_A1 | Up | 0.0605469581 |
| PubMed_21979375_A2 | Up | 0.3736970575 |
| GSE35957 | Up | 0.1181894469 |
| GSE36640 | Up | 0.0995643096 |
| GSE54402 | Up | 0.1636066725 |
| GSE9593 | Up | 0.8917774649 |
| GSE43922 | Up | 0.0123298334 |
| GSE24585 | Down | -0.1504394375 |
| GSE37065 | Up | 0.1061026171 |
| GSE28863_A1 | Down | -0.2662397423 |
| GSE28863_A2 | Up | 0.4693903060 |
| GSE28863_A3 | Up | 0.1975508592 |
| GSE28863_A4 | Down | -0.0303936871 |
| GSE48662 | Up | 0.0238011116 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024587 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026783 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
