HCSGD entry for PACSIN3
1. General information
| Official gene symbol | PACSIN3 |
|---|---|
| Entrez ID | 29763 |
| Gene full name | protein kinase C and casein kinase substrate in neurons 3 |
| Other gene symbols | SDPIII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IEA ISS | molecular_function |
| GO:0008289 | Lipid binding | IDA | molecular_function |
| GO:0019855 | Calcium channel inhibitor activity | IEA ISS | molecular_function |
| GO:0045806 | Negative regulation of endocytosis | IEA ISS | biological_process |
| GO:0051044 | Positive regulation of membrane protein ectodomain proteolysis | IMP | biological_process |
| GO:0051926 | Negative regulation of calcium ion transport | IEA ISS | biological_process |
| GO:0097320 | Membrane tubulation | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9786644656 | 0.0024101668 | 0.9999902473 | 0.0953954887 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1328965298 |
| GSE13712_SHEAR | Down | -0.9206763226 |
| GSE13712_STATIC | Down | -0.1596155146 |
| GSE19018 | Up | 0.0551170260 |
| GSE19899_A1 | Down | -0.2650221558 |
| GSE19899_A2 | Down | -0.9550114945 |
| PubMed_21979375_A1 | Down | -3.4346770919 |
| PubMed_21979375_A2 | Down | -1.2564289540 |
| GSE35957 | Down | -0.1063511534 |
| GSE36640 | Down | -1.5129567729 |
| GSE54402 | Down | -0.5446108809 |
| GSE9593 | Down | -0.3068665844 |
| GSE43922 | Down | -0.4120716875 |
| GSE24585 | Down | -0.3412049509 |
| GSE37065 | Down | -0.2748478688 |
| GSE28863_A1 | Down | -0.3028737115 |
| GSE28863_A2 | Down | -0.2174577772 |
| GSE28863_A3 | Up | 0.4134688878 |
| GSE28863_A4 | Down | -0.0061379806 |
| GSE48662 | Up | 0.5066162695 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020805 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022858 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023821 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030478 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031829 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
