HCSGD entry for BRF1

1. General information

Official gene symbolBRF1
Entrez ID2972
Gene full nameBRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
Other gene symbolsBRF BRF-1 GTF3B TAF3B2 TAF3C TAFIII90 TF3B90 TFIIIB90 hBRF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000126Transcription factor TFIIIB complexNAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006352DNA-templated transcription, initiationIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006383Transcription from RNA polymerase III promoterTASbiological_process
GO:0006384Transcription initiation from RNA polymerase III promoterTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009303RRNA transcriptionTASbiological_process
GO:0009304TRNA transcriptionTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0017025TBP-class protein bindingIEAmolecular_function
GO:0043488Regulation of mRNA stabilityIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77892423540.78118606060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0474400471
GSE13712_SHEARUp0.1667150850
GSE13712_STATICDown-0.1792341130
GSE19018Up0.0241852388
GSE19899_A1Up0.0088100249
GSE19899_A2Up0.1247262549
PubMed_21979375_A1Down-0.2630977191
PubMed_21979375_A2Up0.0604547494
GSE35957Up0.0529763453
GSE36640Down-0.0238038085
GSE54402Down-0.0035680929
GSE9593Up0.0233588681
GSE43922Up0.0035075872
GSE24585Up0.0086119334
GSE37065Down-0.2059778520
GSE28863_A1Up0.0980785977
GSE28863_A2Up0.1162296220
GSE28863_A3Up0.1597568888
GSE28863_A4Up0.0396488025
GSE48662Up0.1132162920

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT037125CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049633CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.