HCSGD entry for GTF2H4

1. General information

Official gene symbolGTF2H4
Entrez ID2968
Gene full namegeneral transcription factor IIH, polypeptide 4, 52kDa
Other gene symbolsP52 TFB2 TFIIH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000439Core TFIIH complexIEAcellular_component
GO:0000718Nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0004003ATP-dependent DNA helicase activityIEAmolecular_function
GO:0004672Protein kinase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005675Holo TFIIH complexIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairIEA TASbiological_process
GO:0006360Transcription from RNA polymerase I promoterTASbiological_process
GO:0006361Transcription initiation from RNA polymerase I promoterTASbiological_process
GO:0006362Transcription elongation from RNA polymerase I promoterTASbiological_process
GO:0006363Termination of RNA polymerase I transcriptionTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0008353RNA polymerase II carboxy-terminal domain kinase activityIDAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016310PhosphorylationIDAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85410788720.17271425860.99999024730.8046038938

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0715467838
GSE13712_SHEARDown-0.2944309296
GSE13712_STATICDown-0.2751826740
GSE19018Down-0.0737089710
GSE19899_A1Down-0.3232137465
GSE19899_A2Up0.0873300802
PubMed_21979375_A1Up2.1289210426
PubMed_21979375_A2Down-0.3038923201
GSE35957Down-0.4225484592
GSE36640Down-0.1136030414
GSE54402Down-0.0050649248
GSE9593Down-0.5592557414
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1711164102

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042111CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.