HCSGD entry for GSTM4
1. General information
| Official gene symbol | GSTM4 |
|---|---|
| Entrez ID | 2948 |
| Gene full name | glutathione S-transferase mu 4 |
| Other gene symbols | GSTM4-4 GTM4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004364 | Glutathione transferase activity | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006749 | Glutathione metabolic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0042178 | Xenobiotic catabolic process | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043295 | Glutathione binding | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9755692071 | 0.0128983929 | 0.9999902473 | 0.2239436675 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0593203086 |
| GSE13712_SHEAR | Down | -0.0803815513 |
| GSE13712_STATIC | Down | -0.2562792991 |
| GSE19018 | Down | -0.0664647621 |
| GSE19899_A1 | Down | -0.2326528559 |
| GSE19899_A2 | Down | -0.8109889196 |
| PubMed_21979375_A1 | Down | -0.9165689447 |
| PubMed_21979375_A2 | Down | -1.1153824049 |
| GSE35957 | Down | -0.5931846551 |
| GSE36640 | Down | -0.0501065099 |
| GSE54402 | Down | -0.7096809069 |
| GSE9593 | Down | -0.0730040105 |
| GSE43922 | Down | -1.2600694735 |
| GSE24585 | Up | 0.0406639116 |
| GSE37065 | Up | 0.1771381966 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2594054144 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
| Glutathione Sulfonic Acid | DB03003 | EXPT01662 |
| S-Octylglutathione | DB03032 | EXPT01665 |
| Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine | DB03597 | EXPT01826 |
| 1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane | DB03706 | EXPT01354 |
| S-Hexylglutathione | DB04132 | EXPT01664 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001461 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
