HCSGD entry for GSTM1

1. General information

Official gene symbolGSTM1
Entrez ID2944
Gene full nameglutathione S-transferase mu 1
Other gene symbolsGST1 GSTM1-1 GSTM1a-1a GSTM1b-1b GTH4 GTM1 H-B MU MU-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004364Glutathione transferase activityIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006749Glutathione metabolic processIDAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0018916Nitrobenzene metabolic processIDAbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0042178Xenobiotic catabolic processIDAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043295Glutathione bindingIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070458Cellular detoxification of nitrogen compoundIDAbiological_process
GO:1901687Glutathione derivative biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34639693780.01120548230.99999024730.2091769504

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2416186974
GSE13712_SHEARDown-0.6020392903
GSE13712_STATICDown-0.8651321397
GSE19018Down-0.3230827245
GSE19899_A1Down-0.7752502108
GSE19899_A2Down-0.3949889855
PubMed_21979375_A1Down-1.7562874780
PubMed_21979375_A2Down-0.7947352964
GSE35957Up0.4553881173
GSE36640Up1.1793971906
GSE54402Down-1.2736182598
GSE9593Up0.3953156661
GSE43922Down-0.1849376089
GSE24585Down-0.0109036807
GSE37065Up0.3425984948
GSE28863_A1Up0.6263756783
GSE28863_A2Up0.3533934259
GSE28863_A3Down-0.1857513542
GSE28863_A4Down-0.0424412546
GSE48662Up0.2429531126

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlutathioneDB00143 NUTR00029 | EXPT01650
(9r,10r)-9-(S-Glutathionyl)-10-Hydroxy-9,10-DihydrophenanthreneDB01834 EXPT01641
Zinc TrihydroxideDB02165 EXPT03289
Glutathione S-(2,4 Dinitrobenzene)DB02458 EXPT01572 | DB04412
FluorotryptophaneDB03314 EXPT01505
(9s,10s)-9-(S-Glutathionyl)-10-Hydroxy-9,10-DihydrophenanthreneDB04187 EXPT01642

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.