HCSGD entry for GRP
1. General information
| Official gene symbol | GRP |
|---|---|
| Entrez ID | 2922 |
| Gene full name | gastrin-releasing peptide |
| Other gene symbols | BN GRP-10 preproGRP proGRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | NAS | molecular_function |
| GO:0005184 | Neuropeptide hormone activity | IDA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2153926295 | 0.9721785836 | 0.8935261856 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0224944569 |
| GSE13712_SHEAR | Up | 0.0675393923 |
| GSE13712_STATIC | Up | 0.0569324508 |
| GSE19018 | Up | 0.3376544755 |
| GSE19899_A1 | Up | 0.0221038680 |
| GSE19899_A2 | Up | 0.1554276378 |
| PubMed_21979375_A1 | Up | 0.0944661295 |
| PubMed_21979375_A2 | Up | 0.1932763844 |
| GSE35957 | Up | 0.3152018191 |
| GSE36640 | Up | 0.0908549428 |
| GSE54402 | Up | 0.0847729459 |
| GSE9593 | Up | 0.1082443674 |
| GSE43922 | Up | 0.1434640112 |
| GSE24585 | Up | 0.1375665474 |
| GSE37065 | Down | -0.0607316021 |
| GSE28863_A1 | Down | -0.0736624836 |
| GSE28863_A2 | Up | 0.0755127042 |
| GSE28863_A3 | Up | 0.1687539933 |
| GSE28863_A4 | Up | 0.0713577466 |
| GSE48662 | Up | 0.1593192668 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26780458 | Gastrin-Releasing Peptide Receptor Knockdown Induces Senescence in Glioblastoma Cells |
| 26780458 | The activation of gastrin-releasing peptide receptors (GRPR) stimulates GBM cell proliferation, whereas GRPR antagonists induce antiproliferative effects in in vitro and in vivo experimental models of GBM |
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