HCSGD entry for GRM2

1. General information

Official gene symbolGRM2
Entrez ID2912
Gene full nameglutamate receptor, metabotropic 2
Other gene symbolsGLUR2 GPRC1B MGLUR2 mGlu2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001641Group II metabotropic glutamate receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEA TASmolecular_function
GO:0005246Calcium channel regulator activityIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007194Negative regulation of adenylate cyclase activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008066Glutamate receptor activityTASmolecular_function
GO:0014047Glutamate secretionIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030424AxonIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0042734Presynaptic membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67261074810.82563230500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1038562404
GSE13712_SHEARDown-0.0614207495
GSE13712_STATICDown-0.1987239189
GSE19018Down-0.0201311451
GSE19899_A1Up0.0543731176
GSE19899_A2Down-0.0352469151
PubMed_21979375_A1Up0.0587446745
PubMed_21979375_A2Down-0.0643896495
GSE35957Up0.2044055545
GSE36640Up0.0306024613
GSE54402Up0.0266726259
GSE9593Up0.0503907657
GSE43922Up0.0649216551
GSE24585Up0.3362455221
GSE37065Down-0.0093142392
GSE28863_A1Up0.1245010820
GSE28863_A2Up0.1609201091
GSE28863_A3Up0.0686557816
GSE28863_A4Down-0.0385118050
GSE48662Down-0.0546609729

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LY2140023DB05096 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.