HCSGD entry for FHOD1
1. General information
| Official gene symbol | FHOD1 |
|---|---|
| Entrez ID | 29109 |
| Gene full name | formin homology 2 domain containing 1 |
| Other gene symbols | FHOS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IDA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007015 | Actin filament organization | IEA | biological_process |
| GO:0032059 | Bleb | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0051496 | Positive regulation of stress fiber assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2912189317 | 0.2654821549 | 0.9900739636 | 0.9867933362 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3112460311 |
| GSE13712_SHEAR | Up | 0.1794118367 |
| GSE13712_STATIC | Up | 0.0928564991 |
| GSE19018 | Down | -0.1960911332 |
| GSE19899_A1 | Down | -0.0326320331 |
| GSE19899_A2 | Down | -0.8318553513 |
| PubMed_21979375_A1 | Down | -0.5910516142 |
| PubMed_21979375_A2 | Up | 0.0434775883 |
| GSE35957 | Down | -0.3569132837 |
| GSE36640 | Up | 0.2239801369 |
| GSE54402 | Up | 0.3888311238 |
| GSE9593 | Down | -0.5877925899 |
| GSE43922 | Up | 0.0450095725 |
| GSE24585 | Up | 0.1705973622 |
| GSE37065 | Down | -0.1532904861 |
| GSE28863_A1 | Up | 0.1417697366 |
| GSE28863_A2 | Up | 0.4638868489 |
| GSE28863_A3 | Down | -0.1599194970 |
| GSE28863_A4 | Up | 0.0676327258 |
| GSE48662 | Down | -0.3528777328 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-5p | MIMAT0004748 | MIRT038061 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045468 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049791 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
