HCSGD entry for GIT1
1. General information
| Official gene symbol | GIT1 |
|---|---|
| Entrez ID | 28964 |
| Gene full name | G protein-coupled receptor kinase interacting ArfGAP 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | TAS | biological_process |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1104668212 | 0.9119628586 | 0.6876469729 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0618982811 |
| GSE13712_SHEAR | Down | -0.1406075546 |
| GSE13712_STATIC | Down | -0.1240061691 |
| GSE19018 | Down | -0.0962206859 |
| GSE19899_A1 | Down | -0.0027158426 |
| GSE19899_A2 | Up | 0.2236135272 |
| PubMed_21979375_A1 | Up | 0.5359747768 |
| PubMed_21979375_A2 | Up | 0.1492979201 |
| GSE35957 | Up | 0.3618060823 |
| GSE36640 | Up | 0.2115154460 |
| GSE54402 | Up | 0.2644457278 |
| GSE9593 | Up | 0.1868248070 |
| GSE43922 | Up | 0.2981302037 |
| GSE24585 | Down | -0.3282366265 |
| GSE37065 | Up | 0.1783727696 |
| GSE28863_A1 | Up | 0.2135114964 |
| GSE28863_A2 | Up | 0.3723583284 |
| GSE28863_A3 | Up | 0.0089190936 |
| GSE28863_A4 | Down | -0.0339071376 |
| GSE48662 | Up | 0.0403737221 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025756 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-484 | MIMAT0002174 | MIRT042200 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
