HCSGD entry for GRB7
1. General information
| Official gene symbol | GRB7 |
|---|---|
| Entrez ID | 2886 |
| Gene full name | growth factor receptor-bound protein 7 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0010494 | Cytoplasmic stress granule | ISS | cellular_component |
| GO:0017148 | Negative regulation of translation | ISS | biological_process |
| GO:0019901 | Protein kinase binding | IDA | molecular_function |
| GO:0030335 | Positive regulation of cell migration | IDA | biological_process |
| GO:0034063 | Stress granule assembly | ISS | biological_process |
| GO:0035091 | Phosphatidylinositol binding | IDA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1876535998 | 0.9129413358 | 0.8441685866 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0971252394 |
| GSE13712_SHEAR | Up | 0.1937646236 |
| GSE13712_STATIC | Up | 0.2421350325 |
| GSE19018 | Up | 0.2107568250 |
| GSE19899_A1 | Up | 0.1376831090 |
| GSE19899_A2 | Up | 0.0976518613 |
| PubMed_21979375_A1 | Up | 0.0689407751 |
| PubMed_21979375_A2 | Down | -0.1904685896 |
| GSE35957 | Up | 0.0637794242 |
| GSE36640 | Up | 0.1009874035 |
| GSE54402 | Up | 0.1405784109 |
| GSE9593 | Up | 0.1047680930 |
| GSE43922 | Up | 0.0348162981 |
| GSE24585 | Up | 0.5396460630 |
| GSE37065 | Up | 0.1745113249 |
| GSE28863_A1 | Down | -0.1314680813 |
| GSE28863_A2 | Down | -0.0572735742 |
| GSE28863_A3 | Up | 0.3027627325 |
| GSE28863_A4 | Up | 0.1429192491 |
| GSE48662 | Down | -0.2312974177 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016993 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028909 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
