HCSGD entry for GPX2
1. General information
| Official gene symbol | GPX2 |
|---|---|
| Entrez ID | 2877 |
| Gene full name | glutathione peroxidase 2 (gastrointestinal) |
| Other gene symbols | GI-GPx GPRP GPRP-2 GPx-2 GPx-GI GSHPX-GI GSHPx-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001659 | Temperature homeostasis | IEA | biological_process |
| GO:0002862 | Negative regulation of inflammatory response to antigenic stimulus | IEA | biological_process |
| GO:0004602 | Glutathione peroxidase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0009609 | Response to symbiotic bacterium | IEA | biological_process |
| GO:0051702 | Interaction with symbiont | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4227615896 | 0.8514387257 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0092715480 |
| GSE13712_SHEAR | Up | 0.0056126158 |
| GSE13712_STATIC | Up | 0.0811360285 |
| GSE19018 | Up | 0.1314395648 |
| GSE19899_A1 | Up | 0.1605100259 |
| GSE19899_A2 | Up | 0.2640413871 |
| PubMed_21979375_A1 | Down | -0.2187864482 |
| PubMed_21979375_A2 | Up | 0.0867443762 |
| GSE35957 | Up | 0.0678694435 |
| GSE36640 | Down | -0.0549362024 |
| GSE54402 | Down | -0.0810591844 |
| GSE9593 | Up | 0.0264689201 |
| GSE43922 | Up | 0.0158136231 |
| GSE24585 | Up | 0.0509099506 |
| GSE37065 | Up | 0.1441184149 |
| GSE28863_A1 | Down | -0.0436919876 |
| GSE28863_A2 | Down | -0.2528515340 |
| GSE28863_A3 | Up | 0.3853451293 |
| GSE28863_A4 | Down | -0.0293460667 |
| GSE48662 | Up | 0.0560904262 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-3p | MIMAT0000071 | MIRT005746 | Luciferase reporter assay//Quantitative proteomic approach//Western blot | Functional MTI | 21203553 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018920 | Microarray | Functional MTI (Weak) | 18185580 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
