HCSGD entry for TRIM59
1. General information
| Official gene symbol | TRIM59 |
|---|---|
| Entrez ID | 286827 |
| Gene full name | tripartite motif containing 59 |
| Other gene symbols | MRF1 RNF104 TRIM57 TSBF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043124 | Negative regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9971993769 | 0.0002163900 | 0.9999902473 | 0.0258199095 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4436898223 |
| GSE13712_SHEAR | Up | 0.2695023744 |
| GSE13712_STATIC | Up | 0.0892328447 |
| GSE19018 | Up | 0.0125906406 |
| GSE19899_A1 | Down | -3.2069915715 |
| GSE19899_A2 | Down | -2.4744010235 |
| PubMed_21979375_A1 | Down | -1.8751802568 |
| PubMed_21979375_A2 | Down | -2.6471404566 |
| GSE35957 | Down | -0.3321076382 |
| GSE36640 | Down | -3.2990663578 |
| GSE54402 | Down | -1.3915289478 |
| GSE9593 | Down | -0.8298214875 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5520589175 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020309 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024373 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025996 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026539 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030898 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031165 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039191 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046150 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
