HCSGD entry for ANK1

1. General information

Official gene symbolANK1
Entrez ID286
Gene full nameankyrin 1, erythrocytic
Other gene symbolsANK SPH1 SPH2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005198Structural molecule activityNASmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonNAScellular_component
GO:0005886Plasma membraneIDA NAScellular_component
GO:0006779Porphyrin-containing compound biosynthetic processIEAbiological_process
GO:0006887ExocytosisNASbiological_process
GO:0006888ER to Golgi vesicle-mediated transportIDAbiological_process
GO:0007010Cytoskeleton organizationNASbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008093Cytoskeletal adaptor activityIDA TASmolecular_function
GO:0010638Positive regulation of organelle organizationIEAbiological_process
GO:0014731Spectrin-associated cytoskeletonIDAcellular_component
GO:0015672Monovalent inorganic cation transportIEAbiological_process
GO:0016323Basolateral plasma membraneNAScellular_component
GO:0016529Sarcoplasmic reticulumIEAcellular_component
GO:0019899Enzyme bindingIPI TASmolecular_function
GO:0030018Z discIEAcellular_component
GO:0030507Spectrin bindingIDA IPI NASmolecular_function
GO:0030673AxolemmaIEAcellular_component
GO:0030863Cortical cytoskeletonIEAcellular_component
GO:0031430M bandIEAcellular_component
GO:0042383SarcolemmaIEAcellular_component
GO:0045199Maintenance of epithelial cell apical/basal polarityTASbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0048821Erythrocyte developmentIEAbiological_process
GO:0051117ATPase bindingIPImolecular_function
GO:0072661Protein targeting to plasma membraneIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36748257290.70395269940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0289058547
GSE13712_SHEARUp0.0121396489
GSE13712_STATICDown-0.1161981208
GSE19018Down-0.0646172573
GSE19899_A1Up0.0015787663
GSE19899_A2Down-0.0587607628
PubMed_21979375_A1Down-0.0527432358
PubMed_21979375_A2Down-0.0997868108
GSE35957Up0.0358340326
GSE36640Up1.4955955531
GSE54402Down-0.0848048747
GSE9593Up0.1975364535
GSE43922Down-0.2495605029
GSE24585Down-0.3513853968
GSE37065Up0.0620894248
GSE28863_A1Up0.1907010365
GSE28863_A2Up0.2187527599
GSE28863_A3Up0.2882209943
GSE28863_A4Up0.1269753549
GSE48662Up0.2239102565

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.