HCSGD entry for DOK7
1. General information
| Official gene symbol | DOK7 |
|---|---|
| Entrez ID | 285489 |
| Gene full name | docking protein 7 |
| Other gene symbols | C4orf25 CMS1B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005158 | Insulin receptor binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007528 | Neuromuscular junction development | IEA | biological_process |
| GO:0019901 | Protein kinase binding | IDA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031594 | Neuromuscular junction | IEA | cellular_component |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0043113 | Receptor clustering | IEA | biological_process |
| GO:0061098 | Positive regulation of protein tyrosine kinase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7052138673 | 0.6055020858 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1651211422 |
| GSE13712_SHEAR | Down | -0.0390092011 |
| GSE13712_STATIC | Down | -0.2533572190 |
| GSE19018 | Down | -0.0266623340 |
| GSE19899_A1 | Up | 0.0111372467 |
| GSE19899_A2 | Up | 0.0760436435 |
| PubMed_21979375_A1 | Up | 0.2081884975 |
| PubMed_21979375_A2 | Down | -0.1939809854 |
| GSE35957 | Up | 0.2952804332 |
| GSE36640 | Down | -0.0781037957 |
| GSE54402 | Up | 0.0176578149 |
| GSE9593 | Up | 0.0006933843 |
| GSE43922 | Up | 0.1220204909 |
| GSE24585 | Down | -0.0063118909 |
| GSE37065 | Down | -0.0417601169 |
| GSE28863_A1 | Down | -0.1479592560 |
| GSE28863_A2 | Down | -0.0175247397 |
| GSE28863_A3 | Up | 0.3026642712 |
| GSE28863_A4 | Up | 0.0830978057 |
| GSE48662 | Up | 0.1312874022 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019810 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022616 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
