HCSGD entry for KANSL1
1. General information
| Official gene symbol | KANSL1 |
|---|---|
| Entrez ID | 284058 |
| Gene full name | KAT8 regulatory NSL complex subunit 1 |
| Other gene symbols | CENP-36 KDVS KIAA1267 MSL1v1 NSL1 hMSL1v1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000123 | Histone acetyltransferase complex | IDA IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0043981 | Histone H4-K5 acetylation | IDA | biological_process |
| GO:0043982 | Histone H4-K8 acetylation | IDA | biological_process |
| GO:0043984 | Histone H4-K16 acetylation | IDA | biological_process |
| GO:0043995 | Histone acetyltransferase activity (H4-K5 specific) | IDA | molecular_function |
| GO:0043996 | Histone acetyltransferase activity (H4-K8 specific) | IDA | molecular_function |
| GO:0046972 | Histone acetyltransferase activity (H4-K16 specific) | IDA | molecular_function |
| GO:0071339 | MLL1 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5936550891 | 0.3500300027 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2689682033 |
| GSE13712_SHEAR | Up | 0.1995044504 |
| GSE13712_STATIC | Down | -0.2650337725 |
| GSE19018 | Up | 0.0252898445 |
| GSE19899_A1 | Up | 0.0095312500 |
| GSE19899_A2 | Down | -0.3039300339 |
| PubMed_21979375_A1 | Down | -0.1582861706 |
| PubMed_21979375_A2 | Down | -0.0060995373 |
| GSE35957 | Down | -0.3095037665 |
| GSE36640 | Down | -0.3427589596 |
| GSE54402 | Down | -0.0381024797 |
| GSE9593 | Down | -0.5853322321 |
| GSE43922 | Down | -0.0154081292 |
| GSE24585 | Up | 0.7400322189 |
| GSE37065 | Up | 0.0150536179 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0102845688 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020287 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025982 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044368 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045617 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046344 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050951 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
