HCSGD entry for XCR1

1. General information

Official gene symbolXCR1
Entrez ID2829
Gene full namechemokine (C motif) receptor 1
Other gene symbolsCCXCR1 GPR5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004950Chemokine receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIEAbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0051209Release of sequestered calcium ion into cytosolIEAbiological_process
GO:0070098Chemokine-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24651377990.96359361730.93497387431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0558862204
GSE13712_SHEARDown-0.0267608670
GSE13712_STATICUp0.1367296450
GSE19018Up0.2879875448
GSE19899_A1Up0.0260425754
GSE19899_A2Up0.1329079923
PubMed_21979375_A1Up0.0061821889
PubMed_21979375_A2Up0.0574170837
GSE35957Up0.0091408005
GSE36640Up0.0177117984
GSE54402Up0.0760845779
GSE9593Up0.1517285052
GSE43922Up0.0242141093
GSE24585Up0.0177723516
GSE37065Up0.3593041938
GSE28863_A1Up0.1696799872
GSE28863_A2Up0.3343122587
GSE28863_A3Down-0.0924223713
GSE28863_A4Up0.0825153279
GSE48662Up0.1407256551

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.