HCSGD entry for SLCO1B3

1. General information

Official gene symbolSLCO1B3
Entrez ID28234
Gene full namesolute carrier organic anion transporter family, member 1B3
Other gene symbolsHBLRR LST-2 LST-3TM13 LST3 OATP-8 OATP1B3 OATP8 SLC21A8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0008206Bile acid metabolic processTASbiological_process
GO:0008514Organic anion transmembrane transporter activityTASmolecular_function
GO:0015711Organic anion transportTASbiological_process
GO:0015721Bile acid and bile salt transportTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043252Sodium-independent organic anion transportTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62776339040.74949955170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0654266766
GSE13712_SHEARDown-0.1279951072
GSE13712_STATICUp0.1422559646
GSE19018Down-0.0224424951
GSE19899_A1Up0.1130699378
GSE19899_A2Up0.0146973218
PubMed_21979375_A1Down-0.0515097487
PubMed_21979375_A2Up0.2414255483
GSE35957Up0.2852183453
GSE36640Up0.0329458731
GSE54402Up0.1341270064
GSE9593Up0.0431728500
GSE43922Up0.1477252157
GSE24585Down-0.0705005211
GSE37065Down-0.0603983092
GSE28863_A1Down-0.0669979755
GSE28863_A2Down-0.0874539958
GSE28863_A3Up0.0651119249
GSE28863_A4Down-0.1129782175
GSE48662Up0.0067697952

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

RifampicinDB01045 APRD00207 | EXPT02777
ClarithromycinDB01211 APRD00181

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.