HCSGD entry for GPC1
1. General information
| Official gene symbol | GPC1 |
|---|---|
| Entrez ID | 2817 |
| Gene full name | glypican 1 |
| Other gene symbols | glypican |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0005507 | Copper ion binding | IDA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA ISS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006024 | Glycosaminoglycan biosynthetic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0014037 | Schwann cell differentiation | ISS | biological_process |
| GO:0017134 | Fibroblast growth factor binding | ISS | molecular_function |
| GO:0030200 | Heparan sulfate proteoglycan catabolic process | IDA | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030204 | Chondroitin sulfate metabolic process | TAS | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0032288 | Myelin assembly | ISS | biological_process |
| GO:0040037 | Negative regulation of fibroblast growth factor receptor signaling pathway | ISS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0043236 | Laminin binding | ISS | molecular_function |
| GO:0043395 | Heparan sulfate proteoglycan binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045121 | Membrane raft | IDA ISS | cellular_component |
| GO:2001016 | Positive regulation of skeletal muscle cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1495471487 | 0.0857899130 | 0.7739344278 | 0.5567249260 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1794932121 |
| GSE13712_SHEAR | Down | -0.1411908586 |
| GSE13712_STATIC | Up | 0.8161844212 |
| GSE19018 | Up | 0.6932404112 |
| GSE19899_A1 | Down | -1.3868169214 |
| GSE19899_A2 | Down | -0.6768555985 |
| PubMed_21979375_A1 | Down | -1.0710295327 |
| PubMed_21979375_A2 | Up | 0.3180826715 |
| GSE35957 | Up | 0.4997808224 |
| GSE36640 | Up | 0.2743644771 |
| GSE54402 | Down | -1.1590027963 |
| GSE9593 | Up | 0.2495547924 |
| GSE43922 | Down | -0.4878190020 |
| GSE24585 | Down | -0.0902828446 |
| GSE37065 | Down | -0.2902655170 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.6335281831 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022703 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023811 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
