HCSGD entry for GMFB


1. General information

Official gene symbolGMFB
Entrez ID2764
Gene full nameglia maturation factor, beta
Other gene symbolsGMF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0004860Protein kinase inhibitor activityTASmolecular_function
GO:0004871Signal transducer activityTASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006469Negative regulation of protein kinase activityTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008047Enzyme activator activityTASmolecular_function
GO:0008083Growth factor activityIEAmolecular_function
GO:0042325Regulation of phosphorylationTASbiological_process
GO:0042326Negative regulation of phosphorylationTASbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0045859Regulation of protein kinase activityTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84047649790.07814758180.99999024730.5289078169

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0503129489
GSE13712_SHEARDown-0.1629909713
GSE13712_STATICUp0.2106684593
GSE19018Down-0.6112432492
GSE19899_A1Down-0.4740290379
GSE19899_A2Down-0.2009053463
PubMed_21979375_A1Up0.2323673180
PubMed_21979375_A2Up0.0162580521
GSE35957Up0.3443816115
GSE36640Up0.3018857377
GSE54402Up0.0198599502
GSE9593Up0.1045068623
GSE43922Down-0.3563209367
GSE24585Up0.1176636310
GSE37065Down-0.0227836894
GSE28863_A1Down-0.4232703104
GSE28863_A2Up0.1734085886
GSE28863_A3Down-0.4634384157
GSE28863_A4Down-0.1216104123
GSE48662Down-0.3839705336

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021506Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-30a-5pMIMAT0000087MIRT028672ProteomicsFunctional MTI (Weak)18668040
hsa-miR-24-3pMIMAT0000080MIRT030603MicroarrayFunctional MTI (Weak)19748357
hsa-miR-186-5pMIMAT0000456MIRT044959CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048247CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.