HCSGD entry for GM2A

1. General information

Official gene symbolGM2A
Entrez ID2760
Gene full nameGM2 ganglioside activator
Other gene symbolsGM2-AP SAP-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004563Beta-N-acetylhexosaminidase activityIEAmolecular_function
GO:0005319Lipid transporter activityIEAmolecular_function
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0006687Glycosphingolipid metabolic processTASbiological_process
GO:0006689Ganglioside catabolic processIEAbiological_process
GO:0007611Learning or memoryIEAbiological_process
GO:0009313Oligosaccharide catabolic processIEAbiological_process
GO:0009898Cytoplasmic side of plasma membraneIEAcellular_component
GO:0016004Phospholipase activator activityIEAmolecular_function
GO:0019915Lipid storageIEAbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045179Apical cortexIEAcellular_component
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051345Positive regulation of hydrolase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00664928380.99275397970.21426418091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2866903182
GSE13712_SHEARUp0.0987042883
GSE13712_STATICDown-0.0151368059
GSE19018Up0.5062234351
GSE19899_A1Up0.1768847010
GSE19899_A2Up1.3062392528
PubMed_21979375_A1Up0.5948592201
PubMed_21979375_A2Up0.3221235455
GSE35957Up0.1268828837
GSE36640Up0.7405409440
GSE54402Up0.2217112000
GSE9593Up1.2436486581
GSE43922Up0.4117413753
GSE24585Up0.1249947104
GSE37065Up0.1682569228
GSE28863_A1Down-0.0345869020
GSE28863_A2Up0.6027959112
GSE28863_A3Down-0.1787717705
GSE28863_A4Down-0.1612231973
GSE48662Up0.4355651802

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Platelet Activating FactorDB02261 EXPT02559
Isopropyl AlcoholDB02325 EXPT01912 | DB04402
Lpc-EtherDB03633 EXPT02056
MYRISTIC ACIDDB08231 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.