HCSGD entry for AMT
1. General information
| Official gene symbol | AMT |
|---|---|
| Entrez ID | 275 |
| Gene full name | aminomethyltransferase |
| Other gene symbols | GCE GCST GCVT NKH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004047 | Aminomethyltransferase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006546 | Glycine catabolic process | IEA | biological_process |
| GO:0008483 | Transaminase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9851640515 | 0.0285235439 | 0.9999902473 | 0.3208411111 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3167475931 |
| GSE13712_SHEAR | Down | -0.5377392143 |
| GSE13712_STATIC | Down | -0.6280821159 |
| GSE19018 | Down | -0.0347172941 |
| GSE19899_A1 | Down | -0.0721005070 |
| GSE19899_A2 | Down | -0.0940659153 |
| PubMed_21979375_A1 | Down | -1.1720225538 |
| PubMed_21979375_A2 | Down | -0.4463610166 |
| GSE35957 | Down | -0.3795627057 |
| GSE36640 | Up | 0.1905542077 |
| GSE54402 | Down | -0.5214715521 |
| GSE9593 | Down | -0.0721258056 |
| GSE43922 | Up | 0.0315460166 |
| GSE24585 | Up | 0.2151179382 |
| GSE37065 | Down | -0.0939925832 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2004865466 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Tetrahydrofolic acid | DB00116 | NUTR00056 |
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| 5-methyltetrahydrofolate | DB04789 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018253 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
