HCSGD entry for GLRX
1. General information
| Official gene symbol | GLRX |
|---|---|
| Entrez ID | 2745 |
| Gene full name | glutaredoxin (thioltransferase) |
| Other gene symbols | GRX GRX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0009055 | Electron carrier activity | IEA | molecular_function |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0015038 | Glutathione disulfide oxidoreductase activity | TAS | molecular_function |
| GO:0015949 | Nucleobase-containing small molecule interconversion | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0277585540 | 0.6908673721 | 0.3867829010 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6073946385 |
| GSE13712_SHEAR | Down | -0.1082570692 |
| GSE13712_STATIC | Up | 0.0351901733 |
| GSE19018 | Up | 0.1722859581 |
| GSE19899_A1 | Up | 0.0006212992 |
| GSE19899_A2 | Up | 0.1637163373 |
| PubMed_21979375_A1 | Up | 0.4259503378 |
| PubMed_21979375_A2 | Up | 0.0226972756 |
| GSE35957 | Up | 0.7119895003 |
| GSE36640 | Up | 1.6380709361 |
| GSE54402 | Up | 0.3451340114 |
| GSE9593 | Up | 0.8542963877 |
| GSE43922 | Down | -0.0114756523 |
| GSE24585 | Up | 0.3147248313 |
| GSE37065 | Up | 0.4653668539 |
| GSE28863_A1 | Down | -0.6728319680 |
| GSE28863_A2 | Down | -0.2384998153 |
| GSE28863_A3 | Down | -0.3922255790 |
| GSE28863_A4 | Down | -0.0815955500 |
| GSE48662 | Up | 0.2669350173 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021981 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027076 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028491 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029425 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031719 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
