HCSGD entry for GLRA2

1. General information

Official gene symbolGLRA2
Entrez ID2742
Gene full nameglycine receptor, alpha 2
Other gene symbolsGLR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEA NAScellular_component
GO:0006811Ion transportIDAbiological_process
GO:0007218Neuropeptide signaling pathwayIDAbiological_process
GO:0007416Synapse assemblyIEAbiological_process
GO:0016594Glycine bindingIDA IEAmolecular_function
GO:0016934Extracellular-glycine-gated chloride channel activityIDAmolecular_function
GO:0022824Transmitter-gated ion channel activityIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
GO:1902476Chloride transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84441266290.65946592070.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1251175095
GSE13712_SHEARUp0.0169279352
GSE13712_STATICDown-0.1259367357
GSE19018Up0.1594991366
GSE19899_A1Down-0.1688903939
GSE19899_A2Up0.0898694745
PubMed_21979375_A1Down-0.1561677612
PubMed_21979375_A2Up0.1787949486
GSE35957Down-0.0225334457
GSE36640Down-0.0744282612
GSE54402Down-0.0854147430
GSE9593Down-0.1047294837
GSE43922Up0.0158600504
GSE24585Up0.3674093568
GSE37065Up0.0024742402
GSE28863_A1Down-0.0373605469
GSE28863_A2Down-0.0348666062
GSE28863_A3Up0.0709200663
GSE28863_A4Up0.0260340604
GSE48662Up0.0363879777

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028
PicrotoxinDB00466 APRD00269

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017796MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.