HCSGD entry for BIN1

1. General information

Official gene symbolBIN1
Entrez ID274
Gene full namebridging integrator 1
Other gene symbolsAMPH2 AMPHL SH3P9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0008283Cell proliferationTASbiological_process
GO:0015629Actin cytoskeletonTAScellular_component
GO:0016032Viral processIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0042692Muscle cell differentiationIEAbiological_process
GO:0043196VaricosityIEAcellular_component
GO:0043547Positive regulation of GTPase activityIEAbiological_process
GO:0043679Axon terminusIEAcellular_component
GO:0044300Cerebellar mossy fiberIEAcellular_component
GO:0045807Positive regulation of endocytosisIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0051020GTPase bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67985208770.42584746020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0629235094
GSE13712_SHEARDown-0.6139673985
GSE13712_STATICUp0.0308970294
GSE19018Up0.1460381939
GSE19899_A1Down-0.3635531869
GSE19899_A2Down-0.0690947357
PubMed_21979375_A1Down-0.1065228403
PubMed_21979375_A2Up0.1538503691
GSE35957Down-0.5719426468
GSE36640Up0.0233811521
GSE54402Down-0.0762553828
GSE9593Down-0.0200027761
GSE43922Up0.0317090906
GSE24585Up0.0874222239
GSE37065Down-0.0757102055
GSE28863_A1Up0.1410964566
GSE28863_A2Up0.3451327411
GSE28863_A3Up0.0598865141
GSE28863_A4Down-0.0826860944
GSE48662Up0.2367745320

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018686MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.