HCSGD entry for STK39
1. General information
| Official gene symbol | STK39 |
|---|---|
| Entrez ID | 27347 |
| Gene full name | serine threonine kinase 39 |
| Other gene symbols | DCHT PASK SPAK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | NAS | biological_process |
| GO:0006950 | Response to stress | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0023014 | Signal transduction by phosphorylation | NAS | biological_process |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0043268 | Positive regulation of potassium ion transport | IEA | biological_process |
| GO:0050727 | Regulation of inflammatory response | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9832436686 | 0.0269181262 | 0.9999902473 | 0.3137899646 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3371503479 |
| GSE13712_SHEAR | Down | -0.0468099165 |
| GSE13712_STATIC | Down | -0.0238766532 |
| GSE19018 | Down | -0.3559009530 |
| GSE19899_A1 | Down | -0.5906037334 |
| GSE19899_A2 | Up | 0.0034719945 |
| PubMed_21979375_A1 | Down | -0.5411966231 |
| PubMed_21979375_A2 | Down | -0.3544041266 |
| GSE35957 | Down | -0.1781843032 |
| GSE36640 | Down | -0.1411694554 |
| GSE54402 | Down | -0.1224351037 |
| GSE9593 | Down | -0.1945321106 |
| GSE43922 | Down | -0.1755511007 |
| GSE24585 | Down | -0.3043853323 |
| GSE37065 | Down | -0.0839844479 |
| GSE28863_A1 | Down | -0.1689689687 |
| GSE28863_A2 | Up | 0.3161816280 |
| GSE28863_A3 | Down | -0.3694797731 |
| GSE28863_A4 | Up | 0.0484858654 |
| GSE48662 | Down | -0.2571936835 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26763397 | It also activated the mammalian Ste20-like protein kinase 1 (MST1); however the serine/threonine kinase Akt was downregulated |
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