HCSGD entry for PCSK1N

1. General information

Official gene symbolPCSK1N
Entrez ID27344
Gene full nameproprotein convertase subtilisin/kexin type 1 inhibitor
Other gene symbolsPROSAAS SAAS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002021Response to dietary excessIEAbiological_process
GO:0004866Endopeptidase inhibitor activityTASmolecular_function
GO:0004867Serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005102Receptor bindingTASmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005802Trans-Golgi networkIEAcellular_component
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0010466Negative regulation of peptidase activityTASbiological_process
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0016486Peptide hormone processingIEAbiological_process
GO:0030141Secretory granuleIEAcellular_component
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0052547Regulation of peptidase activityTASbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19092843740.77419742030.84831657661.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1363421561
GSE13712_SHEARDown-0.2180632572
GSE13712_STATICDown-0.1945843280
GSE19018Down-0.0032456861
GSE19899_A1Down-0.0687222563
GSE19899_A2Up0.1983880342
PubMed_21979375_A1Down-0.2343701726
PubMed_21979375_A2Up0.0704397420
GSE35957Up0.0109214727
GSE36640Up0.0412958807
GSE54402Down-0.0262667711
GSE9593Up0.4491986282
GSE43922Up0.1479815201
GSE24585Up0.1572130508
GSE37065Down-0.0155719604
GSE28863_A1Up0.0057077279
GSE28863_A2Up0.1653563284
GSE28863_A3Up0.6570923427
GSE28863_A4Up0.0757161038
GSE48662Up0.3088917131

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-5pMIMAT0000089MIRT049890CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.