HCSGD entry for UTP20
1. General information
| Official gene symbol | UTP20 |
|---|---|
| Entrez ID | 27340 |
| Gene full name | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| Other gene symbols | DRIM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000447 | Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | ISS | biological_process |
| GO:0000472 | Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | ISS | biological_process |
| GO:0000480 | Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | ISS | cellular_component |
| GO:0005730 | Nucleolus | IDA ISS | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0006364 | RRNA processing | IMP | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0030686 | 90S preribosome | ISS | cellular_component |
| GO:0030688 | Preribosome, small subunit precursor | ISS | cellular_component |
| GO:0032040 | Small-subunit processome | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2302082558 | 0.0190420121 | 0.9135099502 | 0.2707429570 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0306281094 |
| GSE13712_SHEAR | Up | 0.3728647662 |
| GSE13712_STATIC | Up | 0.2095691152 |
| GSE19018 | Down | -0.9498501103 |
| GSE19899_A1 | Down | -0.5325728141 |
| GSE19899_A2 | Down | -0.3423370158 |
| PubMed_21979375_A1 | Down | -0.3305549354 |
| PubMed_21979375_A2 | Up | 0.5447756735 |
| GSE35957 | Down | -0.3362804677 |
| GSE36640 | Down | -1.3952884132 |
| GSE54402 | Down | -0.1391887732 |
| GSE9593 | Down | -0.2231566749 |
| GSE43922 | Down | -0.3949574181 |
| GSE24585 | Down | -0.7883635008 |
| GSE37065 | Down | -0.1158742623 |
| GSE28863_A1 | Up | 1.3237477239 |
| GSE28863_A2 | Up | 1.0716386330 |
| GSE28863_A3 | Down | -0.2359476176 |
| GSE28863_A4 | Up | 0.1455009924 |
| GSE48662 | Down | -0.2425014128 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027738 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031895 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1276 | MIMAT0005930 | MIRT035836 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
