HCSGD entry for EIF3K
1. General information
| Official gene symbol | EIF3K |
|---|---|
| Entrez ID | 27335 |
| Gene full name | eukaryotic translation initiation factor 3, subunit K |
| Other gene symbols | EIF3-p28 EIF3S12 HSPC029 M9 MSTP001 PLAC-24 PLAC24 PRO1474 PTD001 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC IDA TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0043022 | Ribosome binding | IEA | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9462518331 | 0.1296364842 | 0.9999902473 | 0.6931062157 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1153400861 |
| GSE13712_SHEAR | Down | -0.2300876306 |
| GSE13712_STATIC | Down | -0.0977531768 |
| GSE19018 | Up | 0.0457272766 |
| GSE19899_A1 | Down | -0.1164377742 |
| GSE19899_A2 | Down | -0.0070201715 |
| PubMed_21979375_A1 | Up | 0.3448476882 |
| PubMed_21979375_A2 | Down | -0.0271114896 |
| GSE35957 | Down | -0.3156043127 |
| GSE36640 | Down | -0.0699432553 |
| GSE54402 | Up | 0.2157183204 |
| GSE9593 | Down | -0.1841396021 |
| GSE43922 | Down | -0.0558265656 |
| GSE24585 | Down | -0.4108648003 |
| GSE37065 | Down | -0.3796945545 |
| GSE28863_A1 | Up | 0.1267515103 |
| GSE28863_A2 | Down | -0.2090856737 |
| GSE28863_A3 | Down | -0.3716149408 |
| GSE28863_A4 | Up | 0.1518994444 |
| GSE48662 | Down | -0.3356330896 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT016103 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031817 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037589 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049261 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
