HCSGD entry for GLE1
1. General information
| Official gene symbol | GLE1 |
|---|---|
| Entrez ID | 2733 |
| Gene full name | GLE1 RNA export mediator homolog (yeast) |
| Other gene symbols | GLE1L LCCS LCCS1 hGLE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005643 | Nuclear pore | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016973 | Poly(A)+ mRNA export from nucleus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9019835303 | 0.0796198131 | 0.9999902473 | 0.5329789166 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0148801300 |
| GSE13712_SHEAR | Down | -0.2613362985 |
| GSE13712_STATIC | Down | -0.1408787235 |
| GSE19018 | Up | 0.2135741857 |
| GSE19899_A1 | Up | 0.1026926650 |
| GSE19899_A2 | Down | -0.3026483650 |
| PubMed_21979375_A1 | Down | -0.1116442453 |
| PubMed_21979375_A2 | Down | -0.5018717585 |
| GSE35957 | Down | -0.3935044330 |
| GSE36640 | Down | -0.5203650159 |
| GSE54402 | Up | 0.0944792706 |
| GSE9593 | Down | -0.2501299847 |
| GSE43922 | Up | 0.0294273035 |
| GSE24585 | Down | -0.2129900504 |
| GSE37065 | Up | 0.0523872546 |
| GSE28863_A1 | Up | 0.0415747896 |
| GSE28863_A2 | Up | 0.2029325586 |
| GSE28863_A3 | Down | -1.0537676054 |
| GSE28863_A4 | Up | 0.1474658826 |
| GSE48662 | Down | -0.2062056132 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020250 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028211 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24581241 | Therapeutic approaches against chronic wounds include, among others, the local application of living cell constructs (LCCs), containing fibroblasts and/or keratinocytes |
| 24581241 | In conclusion, these results may indicate anti-contractile and anti-fibrotic activities of factor(s) secreted by neonatal skin fibroblasts, and more intensely by LCCs on adult donor-derived fibroblasts |
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