HCSGD entry for HPGDS
1. General information
| Official gene symbol | HPGDS |
|---|---|
| Entrez ID | 27306 |
| Gene full name | hematopoietic prostaglandin D synthase |
| Other gene symbols | GSTS GSTS1-1 PGD2 PGDS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004364 | Glutathione transferase activity | IEA | molecular_function |
| GO:0004667 | Prostaglandin-D synthase activity | EXP IDA | molecular_function |
| GO:0005509 | Calcium ion binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006693 | Prostaglandin metabolic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007626 | Locomotory behavior | TAS | biological_process |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019371 | Cyclooxygenase pathway | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7948561491 | 0.6487501881 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0831586826 |
| GSE13712_SHEAR | Up | 0.2231080510 |
| GSE13712_STATIC | Down | -0.0411221930 |
| GSE19018 | Down | -0.0535998857 |
| GSE19899_A1 | Up | 0.0164872892 |
| GSE19899_A2 | Down | -0.2456376267 |
| PubMed_21979375_A1 | Down | -0.0489691476 |
| PubMed_21979375_A2 | Down | -0.2392081439 |
| GSE35957 | Up | 0.0224663496 |
| GSE36640 | Down | -0.0251009366 |
| GSE54402 | Up | 0.1134434491 |
| GSE9593 | Down | -0.0037480758 |
| GSE43922 | Up | 0.0191538524 |
| GSE24585 | Up | 0.1501187987 |
| GSE37065 | Up | 0.1443356228 |
| GSE28863_A1 | Up | 0.0051116554 |
| GSE28863_A2 | Up | 0.0284458537 |
| GSE28863_A3 | Up | 0.0763573254 |
| GSE28863_A4 | Down | -0.1415726149 |
| GSE48662 | Down | -0.0204169098 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
| 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride | DB01897 | EXPT02404 |
| Glycerol | DB04077 | EXPT01027 |
| 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole | DB07613 | - |
| PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE | DB07614 | - |
| Tranilast | DB07615 | - |
| 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid | DB07616 | - |
| 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE | DB07917 | - |
| nocodazole | DB08313 | - |
| 3-(4-nitrophenyl)-1H-pyrazole | DB08695 | - |
| 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | DB08790 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
