HCSGD entry for RNF115
1. General information
| Official gene symbol | RNF115 |
|---|---|
| Entrez ID | 27246 |
| Gene full name | ring finger protein 115 |
| Other gene symbols | BCA2 ZNF364 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | ISS | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7185279055 | 0.0270406861 | 0.9999902473 | 0.3139558447 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0385084386 |
| GSE13712_SHEAR | Down | -0.0250741886 |
| GSE13712_STATIC | Down | -0.0317543550 |
| GSE19018 | Down | -0.0177820450 |
| GSE19899_A1 | Down | -0.8305520668 |
| GSE19899_A2 | Down | -0.8150270625 |
| PubMed_21979375_A1 | Down | -1.8743259702 |
| PubMed_21979375_A2 | Down | -1.1891083022 |
| GSE35957 | Up | 0.2648388397 |
| GSE36640 | Up | 0.6892130166 |
| GSE54402 | Down | -0.0379883201 |
| GSE9593 | Up | 0.5553423315 |
| GSE43922 | Down | -0.9119406706 |
| GSE24585 | Up | 0.3745700423 |
| GSE37065 | Down | -0.0001786115 |
| GSE28863_A1 | Up | 0.1758166937 |
| GSE28863_A2 | Up | 0.0559485452 |
| GSE28863_A3 | Down | -0.4869176435 |
| GSE28863_A4 | Down | -0.3447326877 |
| GSE48662 | Down | -0.2595285806 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041372 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041801 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051949 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
