HCSGD entry for SIT1
1. General information
| Official gene symbol | SIT1 |
|---|---|
| Entrez ID | 27240 |
| Gene full name | signaling threshold regulating transmembrane adaptor 1 |
| Other gene symbols | RP11-331F9.5 SIT SIT-R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002376 | Immune system process | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0019900 | Kinase binding | IPI | molecular_function |
| GO:0042169 | SH2 domain binding | TAS | molecular_function |
| GO:0050863 | Regulation of T cell activation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7149957334 | 0.4203530641 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0438617537 |
| GSE13712_SHEAR | Up | 0.0402223795 |
| GSE13712_STATIC | Up | 0.1001839229 |
| GSE19018 | Up | 0.0493827451 |
| GSE19899_A1 | Down | -0.0565898746 |
| GSE19899_A2 | Up | 0.2230184751 |
| PubMed_21979375_A1 | Down | -0.0006309032 |
| PubMed_21979375_A2 | Down | -0.1003130999 |
| GSE35957 | Up | 0.0186030995 |
| GSE36640 | Up | 0.1661907775 |
| GSE54402 | Up | 0.0387635159 |
| GSE9593 | Up | 0.1834518561 |
| GSE43922 | Up | 0.2062216397 |
| GSE24585 | Down | -0.1554633937 |
| GSE37065 | Up | 0.1166179256 |
| GSE28863_A1 | Down | -0.5604431807 |
| GSE28863_A2 | Down | -0.6373860576 |
| GSE28863_A3 | Up | 0.0866358187 |
| GSE28863_A4 | Up | 0.1333339469 |
| GSE48662 | Up | 0.0085642361 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
