HCSGD entry for C5AR2
1. General information
| Official gene symbol | C5AR2 |
|---|---|
| Entrez ID | 27202 |
| Gene full name | complement component 5a receptor 2 |
| Other gene symbols | C5L2 GPF77 GPR77 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004944 | C5a anaphylatoxin receptor activity | IEA | molecular_function |
| GO:0004982 | N-formyl peptide receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006935 | Chemotaxis | IEA | biological_process |
| GO:0009925 | Basal plasma membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032720 | Negative regulation of tumor necrosis factor production | IMP | biological_process |
| GO:0045177 | Apical part of cell | IDA | cellular_component |
| GO:0090024 | Negative regulation of neutrophil chemotaxis | IMP | biological_process |
| GO:1900165 | Negative regulation of interleukin-6 secretion | IMP | biological_process |
| GO:2000482 | Regulation of interleukin-8 secretion | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1755755025 | 0.7916308575 | 0.8228851140 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0201064812 |
| GSE13712_SHEAR | Down | -0.0106394192 |
| GSE13712_STATIC | Down | -0.0454240849 |
| GSE19018 | Down | -0.0045799348 |
| GSE19899_A1 | Down | -0.0443379081 |
| GSE19899_A2 | Up | 0.2368399644 |
| PubMed_21979375_A1 | Down | -0.1676954401 |
| PubMed_21979375_A2 | Up | 0.0018963390 |
| GSE35957 | Down | -0.0848043587 |
| GSE36640 | Up | 0.2594436043 |
| GSE54402 | Down | -0.0276931164 |
| GSE9593 | Up | 0.0732744951 |
| GSE43922 | Up | 0.1957601589 |
| GSE24585 | Up | 0.4384883122 |
| GSE37065 | Up | 0.1727072734 |
| GSE28863_A1 | Down | -0.3923546185 |
| GSE28863_A2 | Down | -0.1334988763 |
| GSE28863_A3 | Up | 0.0922873349 |
| GSE28863_A4 | Up | 0.7150739872 |
| GSE48662 | Up | 0.0786216015 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
