HCSGD entry for VPS4A
1. General information
| Official gene symbol | VPS4A |
|---|---|
| Entrez ID | 27183 |
| Gene full name | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| Other gene symbols | SKD1 SKD1A SKD2 VPS4 VPS4-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000815 | ESCRT III complex | IDA | cellular_component |
| GO:0000910 | Cytokinesis | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | NAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IDA | biological_process |
| GO:0016197 | Endosomal transport | IMP TAS | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
| GO:0042623 | ATPase activity, coupled | NAS | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2200633487 | 0.7652449489 | 0.9019175229 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0398909422 |
| GSE13712_SHEAR | Down | -0.0916777642 |
| GSE13712_STATIC | Down | -0.0552531560 |
| GSE19018 | Up | 0.1912823045 |
| GSE19899_A1 | Down | -0.0500490736 |
| GSE19899_A2 | Up | 0.6821697319 |
| PubMed_21979375_A1 | Up | 1.3173793683 |
| PubMed_21979375_A2 | Up | 0.3172716382 |
| GSE35957 | Down | -0.4202086947 |
| GSE36640 | Up | 0.0970313012 |
| GSE54402 | Up | 0.4856825522 |
| GSE9593 | Down | -0.1436523033 |
| GSE43922 | Up | 0.0833517868 |
| GSE24585 | Down | -0.2735983168 |
| GSE37065 | Down | -0.2959867195 |
| GSE28863_A1 | Up | 0.0464535734 |
| GSE28863_A2 | Down | -0.0257441853 |
| GSE28863_A3 | Down | -0.1849632998 |
| GSE28863_A4 | Up | 0.0689455824 |
| GSE48662 | Up | 0.2212101535 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025928 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027230 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032063 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037863 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039864 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042970 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
