HCSGD entry for IL37


1. General information

Official gene symbolIL37
Entrez ID27178
Gene full nameinterleukin 37
Other gene symbolsFIL1 FIL1(ZETA) FIL1Z IL-1F7 IL-1H IL-1H4 IL-1RP1 IL-37 IL1F7 IL1H4 IL1RP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005149Interleukin-1 receptor bindingNAS TASmolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61267101170.62758512970.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0288479777
GSE13712_SHEARUp0.0411781371
GSE13712_STATICUp0.0513068577
GSE19018Up0.0717876429
GSE19899_A1Up0.1038221542
GSE19899_A2Up0.2591666701
PubMed_21979375_A1Up0.0130520620
PubMed_21979375_A2Up0.0071405813
GSE35957Up0.0397931197
GSE36640Down-0.0439790873
GSE54402Up0.0523099229
GSE9593Up0.1547461858
GSE43922Up0.0564138085
GSE24585Up0.0981317684
GSE37065Up0.0824426952
GSE28863_A1Down-0.3139493473
GSE28863_A2Down-0.2063745644
GSE28863_A3Up0.3178366536
GSE28863_A4Down-0.1609690063
GSE48662Down-0.4160275338

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016962MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.