HCSGD entry for IL36B


1. General information

Official gene symbolIL36B
Entrez ID27177
Gene full nameinterleukin 36, beta
Other gene symbolsFIL1 FIL1-(ETA) FIL1H FILI-(ETA) IL-1F8 IL-1H2 IL1-ETA IL1F8 IL1H2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005149Interleukin-1 receptor bindingNASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseNASbiological_process
GO:0032755Positive regulation of interleukin-6 productionIEAbiological_process
GO:0045582Positive regulation of T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01893444780.96572386310.33643434551.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0939872479
GSE13712_SHEARDown-0.1512697855
GSE13712_STATICDown-0.1314321168
GSE19018Up0.1016172307
GSE19899_A1Up0.1184905654
GSE19899_A2Up0.3862374962
PubMed_21979375_A1Up1.4460264613
PubMed_21979375_A2Up0.2258351073
GSE35957Up0.1685762500
GSE36640Up0.1227779721
GSE54402Up1.4013897064
GSE9593Up0.2540834383
GSE43922Up0.5556202361
GSE24585Down-0.1364498303
GSE37065Up2.0581680638
GSE28863_A1Down-0.1786314681
GSE28863_A2Up0.0408807655
GSE28863_A3Up0.1880420882
GSE28863_A4Up0.0264930009
GSE48662Up0.0190435066

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.